Bernarda Majc

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Exploring the safety of cannabidiol (CBD): A comprehensive in vitro evaluation of the genotoxic and mutagenic potential of a CBD isolate and extract from Cannabis sativa L

https://doi.org/10.1016/j.biopha.2024.116969 Alja Štern, Matjaž Novak, Katja Kološa, Jurij Trontelj, Sonja Žabkar, Tjaša Šentjurc, Metka Filipič, Bojana ŽeguraCannabidiol (CBD), a naturally occurring cyclic terpenoid found in Cannabis sativa L., is renowned for its diverse pharmacological benefits. Marketed as a remedy for various health issues, CBD products are utilized by patients as a supplementary therapy or post-treatment failure, as well as by…

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EEMGS congress in Rovinj September 2024
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Bojana Žegura, Alja Štern, Matjaž Novak, Martina Štampar, Katja Kološa and Tim Ravnjak presented research work in the frame of CutCancer project at the EEMGS congress in Rovinj (23-27 September) in a form of poster presentation. They presented several posters, entitled »CutCancer project«, »Adverse (geno)toxic effects of bisphenol A and its analogues BPS, BPAP, BPAF,…

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ESTIV congress in Prague June 2024
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Martina Štampar presented research work at the ESTIV congress in Prague (3-6 June) in a form of poster presentation. She presented work, entitled »Hepatic 3D cell models for assessment of genotoxic effects induced by BPA, BPC, BPAP and their complex mixtures«. In the presented study we tested bisphenol A (BPA), which has become a…

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Mini symposium “Challenges in Drug Delivery”
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Mini symposium was organized by Jozef Stefan Institute researcher dr. Nina Kostevšek and hear team to present the work of each researcher and form project ideas to apply together as consortium to EU funding opportunities in the field of cancer research and drug delivery. Researchers came from Institute of Chemical Sciences & Technologies, Nacional Research…

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SU Visit at NIB
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The National Institute of Biology was proud to host Chika Yokota, PhD, Head of Unit of the In Situ Sequencing National Facility at Stockholm University/SciLifeLab in Sweden and a researcher working on our joint CutCancer Project. Barbara Breznik and Metka Novak presented her the new NIB Biotechnological Hub facility and the ongoing activities at…

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The visit of students from EPFL University – Swiss Federal Institute of Technology Lausanne, Switzerland

National Institute of Biology (NIB), Department of genetic toxicology and cancer biology (GEN) hosted a group of Bachelor students from EPFL University – Swiss Federal Institute of Technology Lausanne, Switzerland. Researchers Dr. Matjaž Novak and Dr. Barbara Breznik presented the research groups, the methods and equipment used at the department, and research topics. Additionally, they…

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Patient-derived tumor organoids mimic treatment-induced DNA damage response in glioblastoma

Open access: https://doi.org/10.1016/j.isci.2024.110604 Bernarda Majc, Anamarija Habič, Marta Malavolta, Miloš Vittori, Andrej Porčnik, Roman Bošnjak, Jernej Mlakar, Alenka Matjašič, Andrej Zupan, Marija Skoblar Vidmar, Tamara Lah Turnšek, Aleksander Sadikov, Barbara Breznik, Metka Novak Glioblastoma (GB) is the most common primary malignant brain tumor, characterized by resistance to therapy. Despite aggressive treatment options, GB remains an…

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Genotoxicity Workshop in Swansea
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Eight participants from the National Institute of Biology (NIB) attended a three-day workshop on genotoxicity at Swansea University in June 2024, hosted by Prof. Dr. Shareen Doak. The workshop focused on sharing knowledge and best practices in laboratory techniques, project applications, and genotoxicological research as part of the CutCancer project. Participants explored advanced equipment for…

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NIB Info Day for Bachelor’s and Master’s Students in Laboratory Biomedicine of Faculty of Pharmacy, University of Ljubljana

Is there something better and more satisfying than passing on knowledge to younger generations? Seeing their eyes shine while you talk about all the things you have already done and things that still need to be revealed and explored? As part of the EU CutCancer_twinning project Department of Genetic Toxicology and Cancer Biology hosted Bachelor…

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EACR congress in Rotterdam June 2024

Barbara Breznik presented research work at the EACR congress in Rotterdam (10-13 June) in a form of poster presentation. She presented work, entitled »Utilizing translational platform GlioBank to identify novel molecular signatures of glioblastoma progression«.  Glioblastoma (GBM) is one of the most lethal solid tumors in humans. Currently, GBM is considered incurable and there is…

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