Cancer Biology unit from NIB has visited SciLifeLab, prof. Mats Nilsson group from SU. In tha last year we have worked together on WP4; Uncovering changes in the TME after treatments using spatial and single-cell analyses on tumour organoids. We are learning new state-of-the-art methodology called in situ sequencing (ISS) that enables spatial and single-cell…
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CutCancer team has visited the group of docent dr. Lovisa Lundholm from Stockholm University, Department of Molecular Biosciences, The Wenner-Gren Institute, which is interested in biological and physical factors affecting cellular and molecular effects of ionising radiation. Focus is on DNA damage and repair, chromatin structure, low doses, low dose rates, mixed radiation qualities, fractionation…
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The National Institute of Biology was proud to host Chika Yokota, PhD, Head of Unit of the In Situ Sequencing National Facility at Stockholm University/SciLifeLab in Sweden and a researcher working on our joint CutCancer Project. Barbara Breznik and Metka Novak presented her the new NIB Biotechnological Hub facility and the ongoing activities at…
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Eight participants from the National Institute of Biology (NIB) attended a three-day workshop on genotoxicity at Swansea University in June 2024, hosted by Prof. Dr. Shareen Doak. The workshop focused on sharing knowledge and best practices in laboratory techniques, project applications, and genotoxicological research as part of the CutCancer project. Participants explored advanced equipment for…
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The last two months Tina Kolenc Milavec, a PhD student from the Department of Genetic Toxicology and Cancer Biology at the National Institute of Biology (NIB), spent at University Medical Center in Amsterdam, in the group of Febe van Maldegem. During the expert visit she learnt all about the Imaging Mass Cytometry, a relatively new…
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We are very grateful and happy to have a PhD student Maria Escrivá Conde from SU Stockholm on hands-on training at NIB. Maria came to train NIB researchers to set up the microscopy settings for In Situ Sequencing (ISS) methodology. Planning joint activities further plans for collaborative experiments focused around e.g. ISS methodology and spatial…
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From 12 to 14 December 2023, we continued to build excellence in the support services of the National Institute of Biology (NIB) when three colleagues from the corporate services (two from the project office and one from the institute library) travelled to Amsterdam, where they were hosted by the CutCancer project partner Amsterdam UMC (VUmc).…
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Tumours are complex mixture of a heterogeneous population of cells that possess distinct genetic, morphological, and phenotypic profiles, which can affect tumour development and therapeutic resistance. The success of cancer treatments relies on the comprehension of the heterogeneous and immune hostile tumour microenvironment (TME), further on providing additional possibilities to eliminate its tumour supportive role.…
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Dr. Van Maldegem from VUmc is one of the pioneers in using and developing Imaging Mass Cytometry (IMC) method for cancer research. IMC enables detailed and contextual characterisation of protein expression and is a mass spectrometry-based technique that allows for the immunostaining of up to 40 markers in a single tissue section. Tissue sections of primary…
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