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Innovative Probes of Metalloproteases 2 and 9 for Targeting Brain Tumor Glioblastoma
Blagoj Mukaetov1, 2, 3, Manca Osolin1, Nika Banovšek1, Bernarda Majc1, Anamarija Habič1,4, Metka Novak1, Tamara Lah Turnšek1, Barbara Breznik1 & Laurent Devel3 1National Institute of Biology, Department of Genetic Toxicology and Cancer Biology, 111 Večna pot, 1000 Ljubljana, Slovenia 2Faculty of Chemistry and Chemical Technology, University of Ljubljana, 113 Večna pot, 1000 Ljubljana, Slovenia 3Université Paris-Saclay,…
Read articleChemotherapy affects the metabolism of glioblastoma stem cells differently than glioblastoma differentiated cells
Katrin S. Galun1, Bernarda Majc1, Anamarija Habič1,2, Cornelis J.F. van Noorden1,3, Barbara Breznik1, Miloš Vittori4, Urban Bogataj4, Metka Novak1 1Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Ljubljana, Slovenia; 2The Jožef Stefan International Postgraduate School, Ljubljana, Slovenia; 3Department of Medical Biology, Amsterdam UMC location Academic Medical Center, University of Amsterdam, Amsterdam, The…
Read articlePersonalized in vitro glioblastoma models for evaluation of therapy response and resistance
Bernarda Majc a, Anamarija Habič a,b, Marta Malavolta c, Mateja Mlinar a, Aleksander Sadikov c, Andrej Porčnik d, Jernej Mlakar Marija Skoblar Vidmar f,g, Metka Novak a, Barbara Breznik a a Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Ljubljana, Slovenia b Jožef Stefan Institute, Jožef Stefan International Postgraduate School, Ljubljana, Slovenia c Faculty of Computer and Information Science University of Ljubljana, Artificial Intelligence…
Read articlePatient-derived glioblastoma organoids reveal glioblastoma resistance to standard therapies
Bernarda Majc a, Anamarija Habič a,b, Marta Malavolta c, Aleksander Sadikov c, Andrej Porčnik d, Jernej Mlakar e, Tamara Lah Turnšek a, Metka Novak a, Barbara Breznik a a Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Ljubljana, Slovenia b Jožef Stefan Institute, Jožef Stefan International Postgraduate School, Ljubljana, Slovenia c Faculty of Computer and Information Science University…
Read articleA three-dimensional glioblastoma model for NK cell immunotherapy research
Anamarija Habič a,b, Bernarda Majc a, Milica Perišić Nanut c, Metka Novak a, Barbara Breznik a a Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Ljubljana, Slovenia b Jožef Stefan Institute, Jožef Stefan International Postgraduate School, Ljubljana, Slovenia c Jožef Stefan Institute, Department of Biotechnology, Ljubljana, Slovenia * Correspondence: barbara.breznik@nib.si; Tel.: + 386 (0)59 232 881 Read more
Read articleGlioblastoma patient-derived organoids as a model for discovering novel markers of therapy resistance in the context of tumor microenvironment: potential role of melanoma antigens
Barbara Breznik a, Bernarda Majc b, Anamarija Habič b, Gloria Krapež b, Andrej Porčnik c, Jernej Mlakar d, Tamara Lah Turnšek b, Metka Novak b, Klementina Fon Tacer a a School of Veterinary Medicine, Texas Tech University, Texas Center for Comparative Cancer Research (TC3R), Amarillo, TX b Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Ljubljana, Slovenia c Department of Neurosurgery, University Medical Centre Ljubljana, Ljubljana, Slovenia…
Read articleCombined Toxic Effects of BPA and Its Two Analogues BPAP and BPC in a 3D HepG2 Cell Model
Martina Štampar a, Tim Ravnjak b, Ana-Marija Domijan c, Bojana Žegura a,* a Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, 1000 Ljubljana, Slovenia b Biotechnical Faculty, University of Ljubljana, 1000 Ljubljana, Slovenia c Department of Pharmaceutical Botany, Faculty of Pharmacy and Biochemistry, University of Zagreb, 10000 Zagreb, Croatia * Correspondence: bojana.zegura@nib.si; Tel.: +386-(0)59-232-862b Read more
Read articleAnti-Vimentin Nanobody Decreases Glioblastoma Cell Invasion In Vitro and In Vivo
Alja Zottel 1, Metka Novak 2, Neja Šamec 1, Bernarda Majc 2,3, Sara Colja 1, Mojca Katrašnik 1, Miloš Vittori 4, Barbara Hrastar 2, Ana Rotter 2, Andrej Porčnik 5, Tamara Lah Turnšek 2,3,6, Radovan Komel 1, Barbara Breznik 2, and Ivana Jovčevska 1,* 1 Medical Centre for Molecular Biology, Institute of Biochemistry and Molecular…
Read articleAdverse (geno)toxic effects of bisphenol A and its analogues in hepatic 3D cell model
Marta Sendra a,b, Martina Štampar c, Katarina Fras c, Beatriz Novoa d, Antonio Figueras d, Bojana Žegura c,e,* a Department of Biotechnology and Food Science, Faculty of Sciences, University of Burgos, Plaza Misael Bañuelos, 09001 Burgos, Spain b International Research Center in Critical Raw Materials-ICCRAM, Universidad de Burgos, Plaza Misael Bañuelos s/n, 09001 Burgos, Spain…
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