open access: https://doi.org/10.1158/2159-8290.CD-23-1380 Enfield KSS, Colliver E, Lee C, Magness A, Moore DA, Sivakumar M, Grigoriadis K, Pich O, Karasaki T, Hobson PS, Levi D, Veeriah S, Puttick C, Nye EL, Green M, Dijkstra KK, Shimato M, Akarca AU, Marafioti T, Salgado R, Hackshaw A; TRACERx consortium; Jamal-Hanjani M, van Maldegem F, McGranahan N, Glass…
Read articleopen access: https://doi.org/10.1016/j.cbi.2024.110977 Sanz-Sagué B, Sáenz-Hernández A, Moreno Maldonado AC, Fuentes-García JA, Nuñez JM, Zegura B, Stern A, Kolosa K, Rozman I, Torres TE, Goya GF The applications of magnetic nanoparticles (MNPs) as biocatalysts in different biomedical areas have been evolved very recently. One of the main challenges in this field is to design affective…
Read articleopen access: https://doi.org/10.1016/j.envint.2022.107721 Marta Sendra, Martina Štampar, Katarina Fras, Beatriz Novoa, Antonio Figueras, Bojana Žegura Bisphenol A (BPA) is one of the most widely used and versatile chemical compounds in polymer additives and epoxy resins for manufacturing a range of products for human applications. It is known as endocrine disruptor, however, there is growing evidence…
Read articleopen access: https://www.mdpi.com/2223382 Štampar, M.; Ravnjak, T.; Domijan, A.-M.; Žegura, B. Bisphenol A (BPA) is one of the most commonly used substances in the manufacture of various everyday products. Growing concerns about its hazardous properties, including endocrine disruption and genotoxicity, have led to its gradual replacement by presumably safer analogues in manufacturing plastics. The widespread…
Read articleOpen access: https://www.mdpi.com/2078002 Zottel A, Novak M, Šamec N, Majc B, Colja S, Katrašnik M, Vittori M, Hrastar B, Rotter A, Porčnik A, et al. Glioblastoma is extremely lethal brain cancer. In our research, we investigated the effect of anti-vimentin nanobody Nb79 on glioblastoma cell invasion. The expression of vimentin in glioma tissues and cells was…
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The last two months Tina Kolenc Milavec, a PhD student from the Department of Genetic Toxicology and Cancer Biology at the National Institute of Biology (NIB), spent at University Medical Center in Amsterdam, in the group of Febe van Maldegem. During the expert visit she learnt all about the Imaging Mass Cytometry, a relatively new…
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We need a little bit of all our diverse knowledge to recognize, understand and treat brain cancer so that one day we can say that we have it under control. GlioBank consortium, a Slovenian translational platform for the collection of tissue samples and corresponding tumour models as well as clinical data from patients diagnosed with…
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We are very grateful and happy to have a PhD student Maria Escrivá Conde from SU Stockholm on hands-on training at NIB. Maria came to train NIB researchers to set up the microscopy settings for In Situ Sequencing (ISS) methodology. Planning joint activities further plans for collaborative experiments focused around e.g. ISS methodology and spatial…
Read articleIn this presentation, we will explore the methodology and significance of analyzing In Situ Sequencing (ISS) data in thecontext of colorectal cancer liver metastasis (CRCLM) and glioblastoma (GBM) samples. ISS offers a powerful approachto investigate spatially resolved gene expression patterns within tissues, providing crucial insights into tumormicroenvironments and cellular interactions. We will discuss the principles…
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Iza Rozman, a young researcher at National Institute of Biology (NIB) gave on 11th of April 2024 an oral presentation to graduate and postgraduate students at the Faculty of Pharmacy about the NIB, namely the Department of Genetic Toxicology and Cancer Biology, the CutCancer project, and her career as a young researcher at the institute.…
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