Bernarda Majc

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Hands-on training

Sonja Žabkar and Katarina Fras underwent three-week hands-on training at Swansea University Medical School, Swansea, Wales, where they gained new knowledge on working and handling the in vitro cell co-culture lung model. They saw how to handle the co-cultures in the inserts, such as media change, treating the co-cultures with chemicals, establishing an air-liquid interface (ALI), where the cells are apically exposed to air, harvesting, and fixing the cells for further experiments. They also managed to touch the principles of micronucleus assay with fixed cells and its analysis on the Metafer system.

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ToxLearn4EU Summer School

Within ToxLearn4EU Summer School in Zagreb (3.7. – 14.7.2023) Bojana Žegura gave a lecture on the advanced hepatic in vitro 3D cell models as a novel approach for studying genotoxic activity of chemicals and nanomaterials that was developed and characterised within the HE CutCancer project.

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Expert visit of NIB researchers to Amsterdam Medical Center, VUmc

Metka Novak and Barbara Breznik had an expert visit to Amsterdam University Medical Center, location VUmc from 4-5 July 2023. They gave scientific lecture on NIB research activities, got acquainted with Imaging Mass Cytometry technology and planned further activities on the CutCancer project. They were hosted by research group of Febe Van Mandegem at the Department of Molecular Cell Biology and Immunology to discuss scientific collaboration.

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Patient-derived glioblastoma organoids reveal glioblastoma resistance to standard therapies

Bernarda Majc a, Anamarija Habič a,b, Marta Malavolta c, Aleksander Sadikov c, Andrej Porčnik d, Jernej Mlakar e, Tamara Lah Turnšek a, Metka Novak a, Barbara Breznik a a Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Ljubljana, Slovenia b Jožef Stefan Institute, Jožef Stefan International Postgraduate School, Ljubljana, Slovenia c Faculty of Computer and Information Science University…

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A three-dimensional glioblastoma model for NK cell immunotherapy research

Anamarija Habič a,b, Bernarda Majc a, Milica Perišić Nanut c, Metka Novak a, Barbara Breznik a a Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Ljubljana, Slovenia b Jožef Stefan Institute, Jožef Stefan International Postgraduate School, Ljubljana, Slovenia c Jožef Stefan Institute, Department of Biotechnology, Ljubljana, Slovenia * Correspondence: barbara.breznik@nib.si; Tel.: + 386 (0)59 232 881 Read more

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Expert visit of NIB at Swansea University, UK

Bojana Žegura visited a project partner Shareen Doak at Swansea University Medical School. Bojana gave an oral presentation about the Department of Genetic Toxicology and Cancer Biology, NIB, and the research conducted within the department with the emphasize on genetic toxicology.

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Staff exchange and training of NIB at Swansea University

The staff from the NIB Project Office, the Technology Transfer Office, the Public Relations Office, the Accountancy Department and the Human Resource Office attended the four-day training to gain new knowledge and share best practices to strengthen research management capacity and administrative skills with the main aim to expand the research and innovation capacity at NIB.

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News in the field of radiotherapy and radiobiology: from research to the clinic

The aim of the conference was to give an overview of the research being carried out in Slovenia in the field of radiotherapy and radiobiology. Clinical and preclinical research in the field of treatment of various cancers such as breast cancer, head and neck cancer, lung cancer, colorectal cancer, skin cancer and brain cancer was presented. The research areas included all treatment methods such as chemotherapy, targeted drugs and immunotherapy as well as radiotherapy. In addition to the research, innovations in immunotherapy treatment were also presented, with a focus on combining it with radiotherapy. Metka Novak from NIB gave a presentation on patient-derived glioblastoma organoids and how they can show resistance of glioblastoma to clinical therapies. She presented new features and the complex composition of glioblastoma organoids and explained how organoids provide a clinically relevant culture system for assessing the specific responses of glioblastoma patients to therapy. She also presented the CutCancer project and explained how the findings from this project will enhance scientific excellence and innovation capacity in the field of 3D in vitro cancer research at NIB, through access to cutting-edge technologies such as spatial transcriptomics and proteomics.

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Infoday Horizon Europe Opportunities for Danube Countries

Bojana Žegura, PhD, presented the story of the successful Twinning application "Twinning for excellence to strategically advance research in carcinogenesis and cancer (CutCancer)". She explained what the Twinning project is about, what is expected from Twinning projects, and how the consortium started preparing the proposal. She presented the main objectives of CutCancer project and explained how the project is structured.

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