Bernarda Majc

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A three-dimensional glioblastoma model for NK cell immunotherapy research

Anamarija Habič a,b, Bernarda Majc a, Milica Perišić Nanut c, Metka Novak a, Barbara Breznik a a Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Ljubljana, Slovenia b Jožef Stefan Institute, Jožef Stefan International Postgraduate School, Ljubljana, Slovenia c Jožef Stefan Institute, Department of Biotechnology, Ljubljana, Slovenia * Correspondence: barbara.breznik@nib.si; Tel.: + 386 (0)59 232 881 Read more

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Expert visit of NIB at Swansea University, UK

Bojana Žegura visited a project partner Shareen Doak at Swansea University Medical School. Bojana gave an oral presentation about the Department of Genetic Toxicology and Cancer Biology, NIB, and the research conducted within the department with the emphasize on genetic toxicology.

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Staff exchange and training of NIB at Swansea University

The staff from the NIB Project Office, the Technology Transfer Office, the Public Relations Office, the Accountancy Department and the Human Resource Office attended the four-day training to gain new knowledge and share best practices to strengthen research management capacity and administrative skills with the main aim to expand the research and innovation capacity at NIB.

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News in the field of radiotherapy and radiobiology: from research to the clinic

The aim of the conference was to give an overview of the research being carried out in Slovenia in the field of radiotherapy and radiobiology. Clinical and preclinical research in the field of treatment of various cancers such as breast cancer, head and neck cancer, lung cancer, colorectal cancer, skin cancer and brain cancer was presented. The research areas included all treatment methods such as chemotherapy, targeted drugs and immunotherapy as well as radiotherapy. In addition to the research, innovations in immunotherapy treatment were also presented, with a focus on combining it with radiotherapy. Metka Novak from NIB gave a presentation on patient-derived glioblastoma organoids and how they can show resistance of glioblastoma to clinical therapies. She presented new features and the complex composition of glioblastoma organoids and explained how organoids provide a clinically relevant culture system for assessing the specific responses of glioblastoma patients to therapy. She also presented the CutCancer project and explained how the findings from this project will enhance scientific excellence and innovation capacity in the field of 3D in vitro cancer research at NIB, through access to cutting-edge technologies such as spatial transcriptomics and proteomics.

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Infoday Horizon Europe Opportunities for Danube Countries

Bojana Žegura, PhD, presented the story of the successful Twinning application "Twinning for excellence to strategically advance research in carcinogenesis and cancer (CutCancer)". She explained what the Twinning project is about, what is expected from Twinning projects, and how the consortium started preparing the proposal. She presented the main objectives of CutCancer project and explained how the project is structured.

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TC3R Seminar Series-invited talk

Barbara Breznik from NIB gave an invited talk as part of TC3R Seminar Series at the Texas Tech University, USA. She summarized the work on new advanced 3D tumor models for cancer research and their use for exploring cancer therapeutic resistance. Identification of new cancer vulnerabilities can lead to more efficient cancer treatment in the future. The talk was dedicated to undergraduate and graduate students as well as researchers and faculty to initiate new research collaborations and project discussions.

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Glioblastoma patient-derived organoids as a model for discovering novel markers of therapy resistance in the context of tumor microenvironment: potential role of melanoma antigens

Barbara Breznik a, Bernarda Majc b, Anamarija Habič b, Gloria Krapež  b, Andrej Porčnik c, Jernej Mlakar d, Tamara Lah Turnšek b, Metka Novak b, Klementina Fon Tacer a a School of Veterinary Medicine, Texas Tech University, Texas Center for Comparative Cancer Research (TC3R), Amarillo, TX b Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Ljubljana, Slovenia c Department of Neurosurgery, University Medical Centre Ljubljana, Ljubljana, Slovenia…

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Research Data Management Roadshow meeting

Manaï Meriem, Research Data management (RDM) Specialist and Vlainic Elize, Research Data Management Consultant presented research data management (RDM) at VUmc, which aims to control the entire data management process along the research lifecycle; from study preparation, data acquisition, data processing and statistical analysis, writing and publishing, to archiving and open data.

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