Barbara Breznik from NIB gave an invited talk as part of TC3R Seminar Series at the Texas Tech University, USA. She summarized the work on new advanced 3D tumor models for cancer research and their use for exploring cancer therapeutic resistance. Identification of new cancer vulnerabilities can lead to more efficient cancer treatment in the future. The talk was dedicated to undergraduate and graduate students as well as researchers and faculty to initiate new research collaborations and project discussions.