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Combined Toxic Effects of BPA and Its Two Analogues BPAP and BPC in a 3D HepG2 Cell Model

open access: https://www.mdpi.com/2223382 Štampar, M.; Ravnjak, T.; Domijan, A.-M.; Žegura, B. Bisphenol A (BPA) is one of the most commonly used substances in the manufacture of various everyday products. Growing concerns about its hazardous properties, including endocrine disruption and genotoxicity, have led to its gradual replacement by presumably safer analogues in manufacturing plastics. The widespread…

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Innovative Probes of Metalloproteases 2 and 9 for Targeting Brain Tumor Glioblastoma

Blagoj Mukaetov1, 2, 3, Manca Osolin1, Nika Banovšek1, Bernarda Majc1, Anamarija Habič1,4, Metka Novak1, Tamara Lah Turnšek1, Barbara Breznik1 & Laurent Devel3 1National Institute of Biology, Department of Genetic Toxicology and Cancer Biology, 111 Večna pot, 1000 Ljubljana, Slovenia 2Faculty of Chemistry and Chemical Technology, University of Ljubljana, 113 Večna pot, 1000 Ljubljana, Slovenia 3Université Paris-Saclay,…

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Chemotherapy affects the metabolism of glioblastoma stem cells differently than glioblastoma differentiated cells

Katrin S. Galun1, Bernarda Majc1, Anamarija Habič1,2, Cornelis J.F. van Noorden1,3, Barbara Breznik1, Miloš Vittori4, Urban Bogataj4, Metka Novak1 1Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Ljubljana, Slovenia; 2The Jožef Stefan International Postgraduate School, Ljubljana, Slovenia; 3Department of Medical Biology, Amsterdam UMC location Academic Medical Center, University of Amsterdam, Amsterdam, The…

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Personalized in vitro glioblastoma models for evaluation of therapy response and resistance

Bernarda Majc a,   Anamarija Habič a,b, Marta Malavolta c, Mateja Mlinar a, Aleksander Sadikov c, Andrej Porčnik d, Jernej Mlakar Marija Skoblar Vidmar f,g,  Metka Novak a, Barbara Breznik a a Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Ljubljana, Slovenia b Jožef Stefan Institute, Jožef Stefan International Postgraduate School, Ljubljana, Slovenia c Faculty of Computer and Information Science University of Ljubljana, Artificial Intelligence…

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Patient-derived glioblastoma organoids reveal glioblastoma resistance to standard therapies

Bernarda Majc a, Anamarija Habič a,b, Marta Malavolta c, Aleksander Sadikov c, Andrej Porčnik d, Jernej Mlakar e, Tamara Lah Turnšek a, Metka Novak a, Barbara Breznik a a Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Ljubljana, Slovenia b Jožef Stefan Institute, Jožef Stefan International Postgraduate School, Ljubljana, Slovenia c Faculty of Computer and Information Science University…

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A three-dimensional glioblastoma model for NK cell immunotherapy research

Anamarija Habič a,b, Bernarda Majc a, Milica Perišić Nanut c, Metka Novak a, Barbara Breznik a a Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Ljubljana, Slovenia b Jožef Stefan Institute, Jožef Stefan International Postgraduate School, Ljubljana, Slovenia c Jožef Stefan Institute, Department of Biotechnology, Ljubljana, Slovenia * Correspondence: barbara.breznik@nib.si; Tel.: + 386 (0)59 232 881 Read more

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Glioblastoma patient-derived organoids as a model for discovering novel markers of therapy resistance in the context of tumor microenvironment: potential role of melanoma antigens

Barbara Breznik a, Bernarda Majc b, Anamarija Habič b, Gloria Krapež  b, Andrej Porčnik c, Jernej Mlakar d, Tamara Lah Turnšek b, Metka Novak b, Klementina Fon Tacer a a School of Veterinary Medicine, Texas Tech University, Texas Center for Comparative Cancer Research (TC3R), Amarillo, TX b Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, Ljubljana, Slovenia c Department of Neurosurgery, University Medical Centre Ljubljana, Ljubljana, Slovenia…

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Combined Toxic Effects of BPA and Its Two Analogues BPAP and BPC in a 3D HepG2 Cell Model

 Martina Štampar a, Tim Ravnjak b, Ana-Marija Domijan c, Bojana Žegura a,* a Department of Genetic Toxicology and Cancer Biology, National Institute of Biology, 1000 Ljubljana, Slovenia b Biotechnical Faculty, University of Ljubljana, 1000 Ljubljana, Slovenia c Department of Pharmaceutical Botany, Faculty of Pharmacy and Biochemistry, University of Zagreb, 10000 Zagreb, Croatia * Correspondence: bojana.zegura@nib.si; Tel.: +386-(0)59-232-862b Read more

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