The genetic toxicology group from NIB attended the 7th International Congress of the Croatian Society of Toxicology (CROTOX 2025), taking place in Rab, Croatia between the 5th to 8th of October. Researches from NIB presented their work in two oral presentations and five posters, which are published in the book of abstracts (https://crotox2025.htd.hr/wp-content/uploads/2025/09/bookofabstracts.pdf) .
Oral presentation given by Tim Ravnjak, titled: Cellular responses to nuclear receptor-activating chemicals in HepG2 spheroids: effects on viability, proliferation, and genotoxicity
Oral presentation given by Iza Rozman, titled: Toward the safer use of nanomaterials: (geno)toxicity evaluation of ferrite-based nanoparticles in HepG2 spheroids
Oral presentation given by Martina Štampar, titled: Automated quantitative fluorescence microscopy and image feature analysis for high content in vitro toxicity screening
Poster presentations:
- Assessment of (geno)toxic effects of bisphenol A (BPA) and its analogues bisphenol AP (BPAP) and bisphenol C (BPC) in a 3D in vitro HepG2 cell model
- Adverse (geno)toxic effects of benzo[a]pyrene (B[a]P) and dibenz[a,h]anthracene (DB[a,h]A) in a 3D hepatocellular spheroid model
- Assessing genotoxicity and inflammatory response to benzo[g,h,i]perylene and benzo[b]fluoranthene in a lung co-culture model at the pseudo-air-liquid interface
- Interpreting the metabolomic signals of polycyclic aromatic hydrocarbons (PAHs) in a 3D liver model
- Evaluating the genotoxic potential of bisphenol A (BPA) alternatives in an advanced zebrafish liver-based in vitro model system
- In vitro safety evaluation of clinically used HI-6 and two novel oximes, antidotes in treatment of organophosphate poisoning, in a 3D human liver spheroid model
- Interpreting polycyclic aromatic hydrocarbons (PAH) metabolomic signals in a 3D liver model
Young researchers at NIB, Tim Ravnjak and Iza Rozman also received Young scientists award, which enabled their attendance at the congress by covering their registration and accommodation costs. Additionally, Alja Štern received an award for 2nd best poster presentation.
